Cataloguenumber
PRO-826
Synonyms
RAB11,YL8,Ras-relatedproteinRab-11A,RAB11A.
Introduction
RAB11AispartofthesmallGTPasesuperfamily,Rabfamily.RAB11Aisrelatedwithbothconstitutiveandregulatedsecretorypathways,andtakespartinproteintransport.RAB11Aisawell-known
Markerforproteintrafficking,sorting,andrecyclingintheendosomalpathway.RAB11Aisamainregulatorofmembranedeliveryduringcytokinesis.
Description
RAB11AHumanRecombinantproducedinE.Coliisasingle,non-glycosylated,
polypeptidechaincontaining249aminoacids(1-213a.a.)andhavingamolecularmassof28.1kDa.RAB11Aproteinisfusedtoa36aminoacidHistagatN-terminusandispurifiedbystandardchromatography.
Source
EscherichiaColi.
PhysicalAppearance
Sterilefilteredcolorlesssolution.
Formulation
RAB11AHumansolutioncontaining20mMTris-HClpH-8,1mMDTT,1mMEDTA&20%glycerol.
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Aminoacidsequence
MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQ
MSDRRENDMSPSNNVVPIHVPPTTENKPKVQCC.
Purity
Greaterthan90%asdeterminedbySDS-PAGE.
Usage
Prospec"sproductsarefurnishedfor LABORATORYRESEARCH USE ONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.