Causedbyoneoffourcloselyrelatedvirus
SEROtypesofthegenusFlavivirus,familyFlaviviridae,eachserotypeissufficientlydifferentthatthereisnocross-protectionandepidemicscausedbymultipleserotypes(hyperendemicity)canoccur.IncellcultureexperimentsandmiceMorpholinoantisenseoligoshaveshownspecificactivityagainstDenguevirus.
RecombinantDengueVirusSubtype3producedinInsectCellsisapolypeptidechaincontainingaminoacids281-673andhavingamolecularweightofapproximately50kDa.
DengueEnvelope-3ispurifiedbyproprietarychromatographictechnique.
Insectcells.
Sterilefilteredcolorlesssolution.
DengueEnvelope-3proteinsolutionin1xD-PBS,pH7.4,0.1%Thimerosal,5mMEDTA,1µg/mlofLeupeptin,AprotininandPepstatinA.
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.