Prospec/GM CSF Rat/CYT-395/1mg,Prospec,,Prospec,prospecbio,ProSpec-Tany,prospecbio产品促销 ProSpec重组蛋白,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Prospec/GM CSF Rat/CYT-395/1mg

产品编号：CYT-395

市场价：¥58500.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$2925.00

品牌： Prospec

公司：Prospec-Tany

公司分类：

商品介绍

Cataloguenumber

CYT-395

Synonyms

CSF-2,MGI-1GM,GM-CSF,Pluripoietin-alpha,Molgramostin,Sargramostim.

Introduction

GMCSFisacytokinethatcontrolstheproduction,differentiation,andfunctionofgranulocytesandmacrophages.Theactiveformoftheproteinisfoundextracellularlyasahomodimer.Thisgenehasbeenlocalizedtoaclusterofrelatedgenesatchromosomeregion5q31,whichisknowntobeassociatedwithinterstitialdeletionsinthe5q-syndromeandacutemyelogenousleukemia.Othergenesintheclusterincludethoseencodinginterleukins4,5,and13.
GM-CSFstimulatesthegrowthanddifferentiationofhematopoieticprecursorcellsfromvariouslineages,includinggranulocytes,macrophages,eosinophilsanderythrocytes.

Description

GranulocyteMacrophageColonyStimulatingFactorRatRecombinantproducedinE.Coliisasingle,non-glycosylated,polypeptidechaincontaining128aminoacidsandhavingamolecularmassof14590.65Dalton.GM-CSFRatRecombinantispurifiedbyproprietarychromatographictechniques.

Source

EscherichiaColi.

PhysicalAppearance

SterileFilteredWhitelyophilized(freeze-dried)powder.

Formulation

GM-CSFRatwaslyophilizedwithnoadditives.

Solubility

ItisrecommendedtoreconstitutethelyophilizedGranulocyteMacrophageColonyStimulatingFactorinsterile18MΩ-cmH2Onotlessthan100µg/ml,whichcanthenbefurtherdilutedtootheraqueoussolutions.

StABIlity

LyophilizedGranulocyteMacrophageColonyStimulatingFactoralthoughstableatroomtemperaturefor3weeks,shouldbestoreddesiccatedbelow-18°C.UponreconstitutionGMCSFshouldbestoredat4°Cbetween2-7daysandforfutureusebelow-18°C.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Pleasepreventfreeze-thawcycles.

Purity

Greaterthan95.0%asdeterminedby:
(a)AnalysisbyRP-HPLC.
(b)AnalysisbySDS-PAGE.

Aminoacidsequence

ThesequenceofthefirstfiveN-terminalaminoacidswasdeterminedandwasfoundtobeMet-Ala-Pro-Thr-Arg.

BIOLOGicalActivity

TheED50range=0.001-0.01ng/mlcorrespondingtoaspecificactivityof100,000,000-1,000,000,000IU/mg,determinedbythedosedependentproliferationofmurineMC/9cells.

Usage

Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.

品牌介绍

ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。