Denguefeverisaffectedby1of4closelylinkedvirus
SEROtypesofthegenusFlavivirus,familyFlaviviridae.Onemighthavedenguefeverinfectedbythedifferentserotypevirusaftertheprimaryinfection.Detectionofparticularantibodiestodenguevirusesisusedforthediagnosisinclinic.Recently,lateralflowrapidtestproductshavebecomeamostsuitableandknownmethodintheclinicaldiagnosis.Though,thereisdifficultyformanufacturerstohavethedengueantigenswithawholecoverageforDengueIgG&IgMrecognitionforall4serotypeinfectionsaswellaswithcolloidgoldbinding
ABIlity.8dengueantigenshavebeenestablishedforthelateralflowproductswhicharewelldefinedfortheircoverageofdengueIgG&IgMrecognition.Theresearchercanselecttheproductsbelowbasedontheirownspecificapplication.
RecombinantDengueVirusSubtype2Envelope32kDa,producedinE.coli,aminoacids45-297andfusedtoa6xHisTag,containingdomainsI+IIofthedengueenvelope.
E.coli.
Purifiedbyproprietarychromatographictechnique.
Proteinis>95%pureasdeterminedby12%PAGE(coomassiestaining).
Phosphatebuffer.
DengueEnvelope-232kDaalthoughstableat4°Cfor1week,shouldbestoredbelow-18°C.Pleasepreventfreezethawcycles.
Canbeusedforimmunoassay.
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.