Cataloguenumber
ANT-355
Synonyms
MRG,BLBP,FABPB,B-FABP,DKFZp547J2313,Fattyacid-bindingproteinbrain,Fattyacid-bindingprotein7,Brainlipid-bindingprotein,Mammary-derivedgrowthinhibitorrelated,FABP7.
Type
MouseAntiHumanMonoclonal.
Introduction
FABP7isabrainfattyacidbindingprotein.Fattyacidbindingproteins(FABPs)areafamilyofsmall,highlyconserved,cytoplasmicproteinsthatbindlong-chainfattyacidsandotherhydrophobicligands.FABPsareareinovlvedinfattyaciduptake,transport,andmetabolism.FABP7isexpressedinr
ADIalgliabytheactivationofNotchreceptorsandbindsDHAwiththehighestaffinityamongallofFABPs.FABP7playsanimportantroleintransportofhydrophobicligandwithpotentialmorphogenicactivityduringcnsdevelopment.FABP7isrequiredfortheestablishmentoftheradialglialfibersystemindevelopingbrain,asystemthatisnecessaryforthemigrationofimmatureneuronstoestablishcorticallayers(bysimilarity).
Clone
PAT1D1AT.
Immunogen
Anti-humanFABP7mAbisderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwithrecombinanthumanFABP7aminoacids1-132purifiedfromE.coli.
IgSubclass
MouseIgG2bheavychainandκlightchain.
PurificationMethod
FABP7antibodywaspurifiedfrommouseasciticfluidsbyprotein-Gaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,&0.1%SodiumAzide.
StorageProcedures
Forperiodsupto1monthstoreat4°C,forlongerperiodsoftime,storeat-20°C.Preventfreezethawcycles.
StABIlity/ShelfLife
12monthsat-20°C.1monthat4°C.
Applications
FABP7antibodyhasbeentestedby
ELISAandWesternblotanalysistoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.RecommendeddilutionrangeforWesternblotanalysisis1:1000~2000.Recommendedstartingdilutionis1:1000.
SafetyDataSheet
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.