Prospec/Thyroglobulin Human, Biotin/Thyroglobulin Human, Biotinylated/50µg/PRO-2563-50µg-50µg,Prospec,,Prospec,prospecbio,ProSpec-Tany,生命科学Prospec价格优惠 ProSpec抗体代理,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Prospec/Thyroglobulin Human, Biotin/Thyroglobulin Human, Biotinylated/50µg/PRO-2563-50µg-50µg

产品编号：PRO-2563-50µg-50µg

市场价：¥6000.00

场地：美国(厂家直采)

产品分类：蛋白类>天然蛋白>其它天然蛋白>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$300.00

品牌： Prospec

公司：Prospec-Tany

公司分类：

商品介绍

Catalogue number

PRO-2563

Synonyms

Thyroglobulin, TGN, AITD3, TG.

Introduction

Thyroglobulin (TG) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is produced by the thyroid epithelial cells (thyrocytes) which form spherical follicles. Thyroglobulin is subsequently secreted and stored in the follicular lumen.Patients with Hashimoto"s thyroiditis or Graves" disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, and the may also be elevated in cases of Graves" disease.

Description

Human Thyroglobulin is a biotinylated, glycosylated, polypeptide chain having a total molecular mass of 662 kDa (331 kDa per subunit).

Source

Native, Isolated from human thyroid glands.

Physical Appearance

Sterile Filtered solution.

Formulation

Human Thyroglobulin biotinylated is supplied at a 20mM HEPES buffer pH-7.6, 150mM NaCl and 40% Sucrose (w/v).

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.

Purity

Greater than 80% as determined by SDS-PAGE.

Immunological functions

1.Binds IgG type human auto antibodies.2.Auto antibodies to thyroglobulin recognize conformation dependent epitopes.

3.Functional Streptavidin based ELISA test (analysis of positive/negative samples.)

Safety Data Sheet

SDS

Usage

Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

品牌介绍

ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。