Prospec/CCL28 Rat/Mucosae-Associated Epithelial Chemokine (CCL28) Rat Recombinant/5µg/CHM-278-5µg-5µg,Prospec,,Prospec,prospecbio,ProSpec-Tany,进口Prospec品牌清关代理中国prospecbio公司,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Prospec/CCL28 Rat/Mucosae-Associated Epithelial Chemokine (CCL28) Rat Recombinant/5µg/CHM-278-5µg-5µg

产品编号：CHM-278-5µg-5µg

市场价：¥1000.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>生长因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$50.00

品牌： Prospec

公司：Prospec-Tany

公司分类：

商品介绍

Cataloguenumber

CHM-278

Synonyms

MEC,CCK1,SCYA28,MGC71902,CCL28,C-Cmotifchemokine28,Small-inducIBLecytokineA28,Mucosae-associatedepithelialchemokine,ProteinCCK1.

Introduction

CCL28ispartofthesubfamilyofsmallcytokineCCgenes.CCL28showschemotacticactivityforrestingCD4orCD8Tcellsandeosinophils.CCL28bindstochemokinereceptorsCCR3andCCR10.CCL28isinvolvedinthephysiologyofextracutaneousepithelialtissues,includingdiversemucosalorgans.CCL28mediatesmucosalimmunityinHIVexposureandinfection.CCL28isinvolvedinthepathogenesisofinflammatoryskindiseases.HumanCCL28CDNAencodesa127aminoacidresidueprecursorproteinwithaputative22aminoacidresiduesignalpeptidethatiscleavedtoproducethe105aminoacidresiduematureprotein.HumanandmouseCCL28arehighlyconserved,sharing83%aminoacididentityintheirmatureregions.CCL28sharesthemosthomologywithCCL27/CTACK.HumanandmouseCCL28RNAexpressionwasfoundtobehighestinnormalandpathologiccolonwiththeproteinbeingexpressedbyepithelialcells.HumanCCL28RNAwasalsopresentinnormalandasthmaticlungtissues.

Description

MECRatRecombinantproducedinE.Coliisanon-glycosylated,Polypeptidechaincontaining116aminoacidsandhavingamolecularmassof13.1kDa.TheRatMECispurifiedbyproprietarychromatographictechniques.

Source

EscherichiaColi.

PhysicalAppearance

SterileFilteredWhitelyophilized(freeze-dried)powder.

Formulation

Theproteinwaslyophilizedfroma0.2µmfilteredconcentratedsolutionin20mMPB,pH7.4and150mMNaCl.

Solubility

ItisrecommendedtoreconstitutethelyophilizedMECinsterile18M-cmH₂Onotlessthan100µg/ml,whichcanthenbefurtherdilutedtootheraqueoussolutions.

StABIlity

LyophilizedMECalthoughstableatroomtemperaturefor3weeks,shouldbestoreddesiccatedbelow-18C.UponreconstitutionMECshouldbestoredat4Cbetween2-7daysandforfutureusebelow-18C.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Pleasepreventfreeze-thawcycles.

Purity

Greaterthan95.0%asdeterminedby(a)AnalysisbyRP-HPLC.(b)AnalysisbySDS-PAGE.

Aminoacidsequence

SEAILPIASSCCTEVSHHIPRRLLERVNSCSIQRADGDCDLAAVILHVKRRRICVSPHNPTLKRWMSASEMKNGKENLCPRKKQDSGKDRKGHTPRKHGKHGTRRIHGTHDHEAPR.

BIOLOGicalActivity

Determinedbyitsabilitytochemoattractmurinelymphocytesusingaconcentrationrangeof1.0-10.0ng/ml.

SafetyDataSheet

SDS

Usage

Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.

品牌介绍

ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。