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主营:重组和天然蛋白、细胞因子和生长因子、趋化因子、蛋白激酶、激素和酶、热休克蛋白、病毒抗原、单克隆及多克隆抗体。
℡ 4000-520-616
℡ 4000-520-616
Prospec/Ephrin A4 Human/PRO-498/5µg
产品编号:PRO-498
市  场 价:¥5400.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$270.00
品      牌: Prospec
公      司:Prospec-Tany
公司分类:
Prospec/Ephrin A4 Human/PRO-498/5µg
商品介绍

Cataloguenumber

PRO-498

Synonyms

Ephrin-A4,EPH-relatedreceptortyrosinekinaseligand4,LERK-4,EFNA4,EPLG4,LERK4,EFL4,MGC125826.

Introduction

EphrinA4isamemberoftheephrin(EPH)family.EphrinsandEPH-relatedreceptorscomprisethelargestsubfamilyofreceptorprotein-tyrosinekinases.Basedupontheirstructuresandsequencerelationships,ephrinsaredividedintotheephrin-A(EFNA)class,whichareattachedtothemembranebyaglycosylphosphatidylinositollinkage,andtheephrin-B(EFNB)class,whicharetransmembraneproteins.ClassAephrinsarelinkedtothemembranebyaGPIlinkageandbindprimarilytoEphAreceptors;ClassBephrinscontainamembrane-spanningregionandbindprimarilytoEphBreceptors.
BothephrinsandEphreceptorsarelargelyexpressedthroughouttheectoderm,mesoderm,andendodermofvertebrateembryos.
EFNAbindstotheEPHA2,EPHA4,EPHA5,EPHA6,andEPHA7receptors.
Twotranscriptvariationswhichencodedifferentisoformswereidentifiedthroughsequenceanalysis.DuringdevelopmenttheEphreceptorandtheirmembrane-attachedligands,ephrins,showdiverseexpressionpatterns.
TheephrinsandEPH-relatedreceptorsmediatedevelopmentalevents,principallyinthenervoussystemandinerythropoiesis.ThecriticalrolesofEphandephrinsduringdevelopmentimplyinvolvementofthesegenesincongenitaldisordersaffectingthenervoussystemandothertissues.
EphrinsandEphreceptorsarepossIBLyinvolvedincarcinogenesis.

Description

EphrinA4HumanRecombinantfulllengthproteinexpressedinE.coli,showsa46kDaSDS-PAGE(IncludingGSTtag).TheEphrinA4ispurifiedbyproprietarychromatographictechniques.

Source

EscherichiaColi.

PhysicalAppearance

SterileFilteredclearsolution.

Formulation

EphrinA4proteinin50mMTris-Acetate,pH7.5,1mMEDTAand20%Glycerol.

StABIlity

Storevialat-20°Cto-80°C.Whenstoredattherecommendedtemperature,thisproteinisstablefor12months.
Pleasepreventfreeze-thawcycles.

Applications

ELISA
•InhibitionAssays
•WesternBlotting.

Usage

Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
品牌介绍

ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列,专注于蛋白(重组及合成)生产研发,其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子,生长因子,激素,信号蛋白,病毒抗原等近800种重组蛋白和100多种抗体,是世界上提供蛋白品种最多的公司之一,领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。

 

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