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主营:重组和天然蛋白、细胞因子和生长因子、趋化因子、蛋白激酶、激素和酶、热休克蛋白、病毒抗原、单克隆及多克隆抗体。
℡ 4000-520-616
℡ 4000-520-616
Prospec/SCGB1A1 Human, His/CYT-752/1mg
产品编号:CYT-752
市  场 价:¥104000.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$5200.00
品      牌: Prospec
公      司:Prospec-Tany
公司分类:
Prospec/SCGB1A1 Human, His/CYT-752/1mg
商品介绍

Cataloguenumber

CYT-752

Synonyms

Uteroglobin,Claracellphospholipid-bindingprotein,CCPBP,Claracells10kDasecretoryprotein,CC10,Secretoglobinfamily1Amember1,Urinaryprotein1,UP-1,UP1,Urineprotein1,SCGB1A1,CCSP,UGB,CC16.

Introduction

Uteroglobin(SCGB1A1)whichbelongstotheSecretoglobin(SCGBs)superfamily,isamultifunctionalproteinthatexertsanti-inflammatoryandanti-tumOrigeniceffectsbybindingsmallhydrophobicmoleculessuchasphospholipidsandprostaglandins.Uteroglobinisinvolvedinnumerousfunctionsincludinganti-inflammation,inhibitionofphospholipaseA2andthesequesteringofhydrophobicligands.SCGB1A1isexpressedbyClaracells,thenon-ciliated,non-mucoussecretorycellspredominantinlungbronchioles,andbyotherepitheliawhichcommunicatewiththeexternalenvironment.Ontopofsequesteringpro-inflammatorymediatorsandcarcinogens,Uteroglobinisimplicatedintheinhibitionofcellmigrationandinvasion,plateletaggregation,andTcelldifferentiation.SCGB1A1genedefectsareassociatedwithasusceptibilitytoasthma.

Description

UteroglobinHumanRecombinantproducedinE.Coliisasingle,non-glycosylated,polypeptidechaincontaining80aminoacidsandincludinga10a.aN-terminalHistag. Thetotalmolecularmassis9.2kDa(calculated).

Source

EscherichiaColi.

PhysicalAppearance

FilteredWhitelyophilized(freeze-dried)powder.

Formulation

Filtered(0.4µm)andlyophilizedfrom0.5mg/mlin0.05Mphosphatebufferand0.075MNaCl,pH7.4.

Solubility

Itisrecommendedtoadd200µldeionizedwatertoprepareaworkingstocksolutionofapproximately0.5mg/mlandletthelyophilizedpelletdissolvecompletely.SCGB1A1isnotsterile!Pleasefiltertheproductbyanappropriatesterilefilterbeforeusingitinthecellculture.

StABIlity

Storelyophilizedproteinat-20°C.Aliquottheproductafterreconstitutiontoavoidrepeatedfreezing/thawingcycles.Reconstitutedproteincanbestoredat4°Cforalimitedperiodoftime;itdoesnotshowanychangeaftertwoweeksat4°C.

Purity

Greaterthan90.0%asdeterminedbySDS-PAGE.

Aminoacidsequence

MKHHHHHHASEICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGAQLKKLVDTLPQKPRESIIKLMEKIAQSSLCN.

Usage

Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
品牌介绍

ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列,专注于蛋白(重组及合成)生产研发,其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子,生长因子,激素,信号蛋白,病毒抗原等近800种重组蛋白和100多种抗体,是世界上提供蛋白品种最多的公司之一,领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。

 

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