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主营:重组和天然蛋白、细胞因子和生长因子、趋化因子、蛋白激酶、激素和酶、热休克蛋白、病毒抗原、单克隆及多克隆抗体。
℡ 4000-520-616
℡ 4000-520-616
Prospec/MCP 1 Antibody/Macrophage/Monocyte Chemotactic & Activating Factor, Mouse Anti-Human/500µg/ANT-119-500µg-500µg
产品编号:ANT-119-500µg-500µg
市  场 价:¥5000.00
场      地:美国(厂家直采)
产品分类: 抗体类>二抗>抗人>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$250.00
品      牌: Prospec
公      司:Prospec-Tany
公司分类:
Prospec/MCP 1 Antibody/Macrophage/Monocyte Chemotactic & Activating Factor, Mouse Anti-Human/500µg/ANT-119-500µg-500µg
商品介绍

Cataloguenumber

ANT-119

Synonyms

SmallinducIBLecytokineA2,CCL2,Monocytechemotacticprotein1,MCP-1,Monocytechemoattractantprotein1,Monocytechemotacticandactivatingfactor,MCAF,MonocytesecretoryproteinJE,HC11,chemokine(C-Cmotif)ligand2,MCP1,SCYA2,GDCF-2,SMC-CF,HSMCR30,MGC9434,GDCF-2HC11.

Type

MouseAntiHumanMonoclonal.

Introduction

Chemokine(C-Cmotif)ligand2(CCL2)isasmallcytokinebelongingtotheCCchemokinefamilythatisalsoknownasmonocytechemotacticprotein-1(MCP-1).Itisfoundatthesiteoftootheruptionandbonedegradation.Inthebone,CCL2isexpressedbymatureosteoclastsandosteoblastsandisunderthecontrolofnuclearfactor?B(NF?B).CCL2recruitsimmunecells,suchasmonocytes,tositesoftissueinjuryandinfection.Thischemokineisproducedasaproteinprecursorcontainingsignalpeptideof23aminoacidsandamaturepeptideof76aminoacids.Itisamonomericpolypeptide,withamolecularweightofapproximately13kDa.AswithmanyotherCCchemokines,CCL2islocatedonchromosome17inhumans.ThecellsurfacereceptorsthatbindCCL2areCCR2andCCR5.

Clone

YNR-HMCAF.

Immunogen

r.HumanMCAF.

IgSubclass

MouseIgG2a.

PurificationMethod

Ionexchange.

Formulation

1mg/mlinPBS(afterreconstitution)ShippingConditionsAntibodyisshippedlyophilizedatambienttemperature.

StorageProcedures

Inlyophilizedform,forlongperiods,storeat4oCinadryenvironment.Afterreconstitution,ifnotintendedforusewithinamonth,aliquotandstoreat-20oC.

Solubility

ReconstitutewithsterileH20.Mixgently,washthesidesofthevialandwait30-60secondsbeforeuse.

Titer

IndirectELISA,usingalkalinephosphatasegoatanti-mouseIg(JacksonLaboratories)1:5,000dilutionwillgive0.3O.Dwithin10minutes.

Applications

DirectELISA,WesternBlot,Immuneprecipitation.

Note

MCAFdoesnotbindtoplasticasgoodasmostproteins-usehigherconcentrationforproperbinding.

SafetyDataSheet

SDS

Usage

Prospec"sproductsarefurnishedforLABORATORYESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
品牌介绍

ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列,专注于蛋白(重组及合成)生产研发,其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子,生长因子,激素,信号蛋白,病毒抗原等近800种重组蛋白和100多种抗体,是世界上提供蛋白品种最多的公司之一,领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。

 

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