Catalogue number
CYT-796
Synonyms
CD116, CDw116, CSF2R, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4,GMR-alpha, CD116 Antigen, CSF2RAX, CSF2RY, CSF2RAY, CSF2RX, Colony StimulatingFactor 2 Receptor Alpha Subunit, GM-CSF Receptor Alpha Subunit, Granulocyte-MacrophageColony-Stimulating Factor Receptor Alpha Chain, Granulocyte-MacrophageColony-Stimulating Factor Receptor Subunit Alpha.
Introduction
GM-CSFReceptor Alpha (CSF2RA) is the alpha subunit of the heterodimeric receptor forcolony stimulating factor 2, a cytokine which controls the production,differentiation, and function of granulocytes and macrophages. CSFR2 is also amember of the cytokine family of receptors. In addition, this gene is found inthe pseudoautosomal region (PAR) of the X and Y chromosomes. Multipletranscript variants encoding various isoforms have been found for this gene, whilesome of the isoforms being membrane-bound and others being soluble. Diseasesassociated with CSF2RA include surfactant metabolism dysfunction, pulmonary 4,and csf2ra-related pulmonary surfactant metabolism dysfunction.
Description
CSF2RA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 324 amino acids (20-320 a.a) and having a molecular mass of 37.2kDa.
CSF2RA is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
CSF2RA protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greaterthan 85.0% as determined by SDS-PAGE.
Safety Data Sheet
Usage
ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.