Cataloguenumber
HOR-254
Synonyms
OT,OXT,OT-NPI,Neurophysin1,MGC126890,MGC126892.
Introduction
HumanOxytocinstimulatesuterinesmoothmusclecontractionsindirectlyandstimulatesthemammaryglandstoincreaselactationwithoutincreasingtheproductionofmilk.
Description
OxytocinHumanSyntheticisasingle,non-glycosylated,polypeptidechaincontaining9aminoacidsandhavingamolecularmassof1007.2Dalton.OxytocinhasamolecularformulaofC43H66N12O12S2.TheOTispurifiedbyproprietarychromatographictechniques.
PhysicalAppearance
SterileFilteredWhitelyophilized(freeze-dried)powder.
Formulation
TheOxytocinwaslyophilizedfromaconcentrated(1mg/ml)solutionwithnoadditives.
Solubility
ItisrecommendedtoreconstitutethelyophilizedOxytocininsterile18MΩ-cmH2Onotlessthan100µg/ml,whichcanthenbefurtherdilutedtootheraqueoussolutions.
LyophilizedOxytocinalthoughstableatroomtemperaturefor3weeks,shouldbestoreddesiccatedbelow-18°C.UponreconstitutionNeurophysin1shouldbestoredat4°Cbetween2-7daysandforfutureusebelow-18°C.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Pleasepreventfreeze-thawcycles.
Purity
Greaterthan99.0%asdeterminedbyRP-HPLC.
Aminoacidsequence
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2.
SpecificActivity
1mgofOxytocinhasactivitygreaterthan480IU/mg.
SafetyDataSheet
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
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