Ganirelixacetateisasyntheticdecapeptidewithhighantago
NISTicactivityagainstnaturallyoccurringgonadotropin-releasinghormone(GnRH).GanirelixacetateisderivedfromnativeGnRHwithsubstitutionsofaminoacidsatpositions1,2,3,6,8,and10toformthefollowingmolecularformulaofthepeptide:N-acetyl-3-(2-napthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-N9,N10-diethyl-D-homoarginyl-L-leucyl-N9,N10-diethyl-L-homoarginyl-L-prolyl-D-alanylamideacetate.ThemolecularweightforGanirelixacetateis1570.4Daltonasananhydrousfreebase.
SterileFilteredcolorlessliquidformulation.
TheGanirelixhormone(0.5mg/ml)contains0.1mgaceticacidand23.5mgmannitolpH-5.
Greaterthan98.0%asdeterminedby:(a)AnalysisbyRP-HPLC.(b)AnalysisbySDS-PAGE.
Ganirelixshouldbestoredbetween2°C-8°Catalltime.DONOTFREEZE.
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.