Prospec/4 1BBL Human, His/4-1BB Ligand Human Recombinant, His Tag/5µg/CYT-649-5µg,Prospec,,Prospec,prospecbio,ProSpec-Tany,Prospec批发，产品货源进口prospecbio现货,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Prospec/4 1BBL Human, His/4-1BB Ligand Human Recombinant, His Tag/5µg/CYT-649-5µg

产品编号：CYT-649-5µg

市场价：¥1000.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$50.00

品牌： Prospec

公司：Prospec-Tany

公司分类：

商品介绍

Cataloguenumber

CYT-649

Synonyms

CD137L,CD137-L,4-1BBL,4-1BBLigand,TNFSF9,TumorNecrosisFactor(ligand)SuperfamilyMember9.

Introduction

4-1BBLisatransmembranecytokinethatispartofthetumornecrosisfactor(TNF)ligandfamily.4-1BBLisabidirectionalsignaltransducerthatperformsasaligandforTNFRSF9,whichisacostimulatoryreceptormoleculeinTlymphocytes.TNFSF9anditsTNFRSF9takepartintheantigenpresentationdevelopmentandinthegenerationofcytotoxicTcells.4-1BBRisabsentfromrestingTlymphocytesbutrapidlyexpresseduponantigenicstimulation.TNFSF9reactivatesanergicTlymphocytesaswellaspromotingTlymphocyteproliferation.4-1BBLigandisneededfortheoptimalCD8responsesinCD8Tcells.4-1BBLisexpressedincarcinomacelllines,andisthoughttobeinvolvedinTcell-tumorcellinteraction.4-1BBLisexpressedbyactivatedBcells,macrophages,dendriticcells,activatedTcells,neuronsandastrocytes.Theinteractionof4-1BBwithTNFRSF9stronglyregulatesimmunityandhasbeenproposedtopreferentiallycontrolTcellresponsesbasedonstudiesinvariousmurin

Description

TNFSF9HumanRecombinantfusedto37aminoacidsHistagatN-terminusproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining222aminoacids(71-254a.a.)andhavingamolecularmassof23.8kDa.TheTNFSF937aaHistagfusionproteinispurifiedbyproprietarychromatographictechniques.

Source

EscherichiaColi.

PhysicalAppearance

SterileFilteredcolorlesssolution.

Formulation

Recombinant4-1BBLsolution(1mg/ml)contains20mMTris-HClbufferpH-8,100mMNaCland20%glycerol.

StABIlity

Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.

Purity

Greaterthan95.0%asdeterminedbySDS-PAGE

Aminoacidsequence

MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSHMREGPELSPDDPAGLLDLRQGMFAQLVAQNVLLIDGPLSWYSDPGLAGVSLTGGLSYKEDTKELVVAKAGVYYVFFQLELRRVVAGEGSGSVSLALHLQPLRSAAGAAALALTVDLPPASSEARNSAFGFQGRLLHLSAGQRLGVHLHTEARARHAWQLTQGATVLGLFRVTPEIPAGLPSPRSE.

SafetyDataSheet

SDS

Usage

Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.

品牌介绍

ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。